产品货号：
Z16388
中文名称：
FMO3抗体
英文名称：
Anti-FMO3 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FMO3 Antibody |
| 指标别名 | Dimethylaniline oxidase 3;FMO 3;FMO form 2;FMO II;FMO3;FMOII;TMAU |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | FMO3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human FMO3. |
| 计算分子量 | 60KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | FMO3 (Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene.The mammalian flavin-containing monooxygenases (FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues.The FMO3 gene contains 1 noncoding and 8 coding exons.And the FMO3 gene is mapped on 1q24.3.Using quantitative RNase protection assays,FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung,and in much greater abundance in adult liver.By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age,FMO1 is the major fetal isoform and FMO3 is the major adult isoform.FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty.Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine.FMO3 metabolizes a number of drugs,including amphetamine,clozapine,deprenyl,metamphetamine,tamoxifen,ethionamide,thiacetazone,and sulindac sulfide. |
| Uniprot ID | P31513 |
| 基因名全称 | Dimethylaniline monooxygenase [N-oxide-forming] 3 |
| 蛋白名全称 | Dimethylaniline monooxygenase [N-oxide-forming] 3 |
| 推荐稀释比 | WB 1:500～1:2000 IHC-P 1:100～1:300 ELISA 1:20000 |
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